Lipase-catalysed ammoniolysis of lipids. A facile synthesis of fatty acid amides

被引：42

作者：

deZoete, MC ^{[1
]}

KockvanDalen, AC ^{[1
]}

vanRantwijk, F ^{[1
]}

Sheldon, RA ^{[1
]}

机构：

[1] DELFT UNIV TECHNOL,DEPT ORGAN CHEM & CATALYSIS,2628 BL DELFT,NETHERLANDS

来源：

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC | 1996年 / 1卷 / 3-6期

关键词：

ammoniolysis; lipase; lipids; fatty acid amides; amides;

D O I：

10.1016/1381-1177(95)00012-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ammoniolysis of triglycerides to the corresponding fatty acid amides is efficiently catalysed by Candida antarctica lipase (Novozym 435). Thus, olive oil gave 90% of nearly pure oleamide after 72 h at 60 degrees C. Jojoba wax was similarly converted into a mixture of cis-11-eicosenamide and erucamide together with cis-11-eicosenol and cis-13-docosenol.

引用

页码：109 / 113

页数：5

共 15 条

[1]

CHEN ST, 1993, SYNTHESIS-STUTTGART, P858

[2] CHEMICAL CHARACTERIZATION OF A FAMILY OF BRAIN LIPIDS THAT INDUCE SLEEP [J].

CRAVATT, BF ;

PROSPEROGARCIA, O ;

SIUZDAK, G ;

GILULA, NB ;

HENRIKSEN, SJ ;

BOGER, DL ;

LERNER, RA .

SCIENCE, 1995, 268 (5216) :1506-1509

[3] A NEW ENZYMATIC-REACTION - ENZYME-CATALYZED AMMONOLYSIS OF CARBOXYLIC ESTERS [J].

DEZOETE, MC ;

KOCKVANDALEN, AC ;

VANRANTWIJK, F ;

SHELDON, RA .

BIOCATALYSIS, 1994, 10 (1-4) :307-316

[4] ESTER AMMONIOLYSIS - A NEW ENZYMATIC-REACTION [J].

DEZOETE, MC ;

DALEN, ACK ;

VANRANTWIJK, F ;

SHELDON, RA .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1993, (24) :1831-1832

[5]

DEZOETE MC, 1995, RECL TRAV CHIM PAY B, V114, P171

[6]

DEZOETE MC, 1995, Patent No. 07359

[7]

GARCIA MJ, 1993, TETRAHEDRON LETT, V34, P6146

[8]

HELDTHANSEN HP, 1989, ACS SYM SER, V389, P158

[9]

ISHII M, 1988, Patent No. 02775

[10]

Kirk O., 1992, BIOCATALYSIS, V6, P127

← 1 2 →