Directed antibody-engineering techniques and their applications in food immunoassays

被引：12

作者：

Markus, Vehniainen ^{[1
]}

Janne, Leivo ^{[1
]}

Urpo, Lamminmaki ^{[1
]}

机构：

[1] Univ Turku, Dept Biochem & Food Chem, FIN-20540 Turku, Finland

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2011年 / 30卷 / 02期

关键词：

Antibody; Directed antibody engineering; Food immunoassay; Food quality; Food safety; Immunoanalysis; Immunodiagnostics; Recombinant antibody; SPECIFICITY HAPTEN RECOGNITION; VARIABLE FRAGMENT ANTIBODY; SITE-SPECIFIC MUTAGENESIS; SINGLE-DOMAIN ANTIBODIES; PHAGE DISPLAY LIBRARY; ESCHERICHIA-COLI; HETEROPHILIC ANTIBODIES; AFFINITY MATURATION; PROTEIN EVOLUTION; CROSS-REACTIVITY;

D O I：

10.1016/j.trac.2011.01.001

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The use of antibodies in immunodiagnostics has achieved new insights with recombinant technologies. This review summarizes the methods used to produce recombinant antibodies and those to tailor their properties. Finally, we address the advantages and the possibilities of recombinant antibodies in immunoanalytical applications through examples with the main focus on applications related to food quality and safety analysis. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：219 / 226

页数：8

共 69 条

[1] Properties of polyclonal, monoclonal, and recombinant antibodies recognizing the organophosphorus pesticide chlorpyrifos-ethyl
Alcocer, MJC
Doyen, C
Lee, HA
Morgan, MRA
[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2000, 48 (09) : 4053 - 4059
[2] OPTIMIZING NUCLEOTIDE MIXTURES TO ENCODE SPECIFIC SUBSETS OF AMINO-ACIDS FOR SEMI-RANDOM MUTAGENESIS
ARKIN, AP
YOUVAN, DC
[J]. BIO-TECHNOLOGY, 1992, 10 (03): : 297 - 300
[3] IN-VITRO EVOLUTION OF A NEUTRALIZING HUMAN-ANTIBODY TO HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 TO ENHANCE AFFINITY AND BROADEN STRAIN CROSS-REACTIVITY
BARBAS, CF
HU, D
DUNLOP, N
SAWYER, L
CABABA, D
HENDRY, RM
NARA, PL
BURTON, DR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (09) : 3809 - 3813
[4] Low-fidelity Pyrococcus furiosus DNA polymerase mutants useful in error-prone PCR -: art. no. e176
Biles, BD
Connolly, BA
[J]. NUCLEIC ACIDS RESEARCH, 2004, 32 (22) : e176
[5] Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity
Boder, ET
Midelfort, KS
Wittrup, KD
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (20) : 10701 - 10705
[6] Use of high-capacity surface with oriented recombinant antibody fragments in a 5-min immunoassay for thyroid-stimulating hormone
Brockmann, Eeva-Christine
Vehniainen, Markus
Pettersson, Kim
[J]. ANALYTICAL BIOCHEMISTRY, 2010, 396 (02) : 242 - 249
[7] Cadwell R C, 1992, PCR Methods Appl, V2, P28, DOI 10.1101/gr.2.1.28
[8] Cloning, expression, and characterization of single-chain variable fragment antibody against mycotoxin deoxynivalenol in recombinant Escherichia coli
Choi, GH
Lee, DH
Min, WK
Cho, YJ
Kweon, DH
Son, DH
Park, K
Seo, JH
[J]. PROTEIN EXPRESSION AND PURIFICATION, 2004, 35 (01) : 84 - 92
[9] MAKING ANTIBODY FRAGMENTS USING PHAGE DISPLAY LIBRARIES
CLACKSON, T
HOOGENBOOM, HR
GRIFFITHS, AD
WINTER, G
[J]. NATURE, 1991, 352 (6336) : 624 - 628
[10] Synthetic antibody libraries focused towards peptide ligands
Cobaugh, Christian W.
Almagro, Juan C.
Pogson, Mark
Iverson, Brent
Georgiou, George
[J]. JOURNAL OF MOLECULAR BIOLOGY, 2008, 378 (03) : 622 - 633

← 1 2 3 4 5 6 7 →