Generation of the CF3 radical from trifluoromethylsulfonium triflate and its trifluoromethylation of styrenes

被引：154

作者：

Zhang, Cheng-Pan ^{[1
]}

Wang, Zong-Ling ^{[1
,2
]}

Chen, Qing-Yun ^{[1
]}

Zhang, Chun-Tao ^{[2
]}

Gu, Yu-Cheng ^{[3
]}

Xiao, Ji-Chang ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

[2] Hunan Univ Chinese Med, Changsha 410208, Hunan, Peoples R China

[3] Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 23期

关键词：

MILD ELECTROPHILIC TRIFLUOROMETHYLATION; SILYL ENOL ETHERS; PERFLUOROALKYL IODIDES; SODIUM DITHIONITE; REAGENTS; CHEMISTRY; KETONES; SULFINATODEHALOGENATION; NUCLEOPHILES; REACTIVITY;

D O I：

10.1039/c1cc11765c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The CF3 radical was generated from the reaction of S-(trifluoromethyl)diphenylsulfonium triflate with Na2S2O4 or HOCH2-SO2Na under suitable conditions without further reduction. Based on this, a method for the synthesis of alpha-trifluoromethylated ketones has been successfully developed.

引用

页码：6632 / 6634

页数：3

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