Controlled monoarylation of dibromoarenes in water with a polymeric palladium catalyst

被引：55

作者：

Uozumi, Y ^{[1
]}

Kikuchi, M ^{[1
]}

机构：

[1] Inst Mol Sci, Okazaki, Aichi 4448787, Japan

来源：

SYNLETT | 2005年 / 11期

关键词：

Suzuki-Miyaura coupling; cross-coupling; biaryl formation; dibromoarenes;

D O I：

10.1055/s-2005-871540

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly selective monoarylation of dibromoarenes was performed via the Suzuki-Miyaura cross-coupling with arylboronic acids with an amphiphilic polystyrene-poly(ethylene glycol) (PS-PEG) resin-supported phosphine-palladium complex in water under heterogeneous conditions to give bromobiaryls in high yields. Introduction of two different aryl groups on a aromatic moiety was achieved in a one-pot reaction by successive addition of two kinds of arylboronic acids under similar conditions. The polymeric palladium catalyst can be readily recovered and recycled.

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收藏

页码：1775 / 1778

页数：4

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