Histidine residue at position 234 of oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae simultaneously influences cyclization, rearrangement, and deprotonation reactions

被引：32

作者：

Wu, TK ^{[1
]}

Liu, YT ^{[1
]}

Chang, CH ^{[1
]}

机构：

[1] Natl Chiao Tung Univ, Dept Biol Sci & Technol, Ctr Interdisciplinary Mol Sci, Hsinchu 300, Taiwan

来源：

CHEMBIOCHEM | 2005年 / 6卷 / 07期

关键词：

cyclization; homology modeling; oxidosqualene cyclase; rearrangement; sterols; terpenoids;

D O I：

10.1002/cbic.200500084

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Histidine Residue at Position 234 of Oxidosqualene-Lanosterol Cyclase from Saccharomyces cerevisiae Simultaneously Influences Cyclization, Rearrangement, and Deprotonation Reactions

引用

页码：1177 / +

页数：6

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