Transposon tools and methods in zebrafish

被引：206

作者：

Kawakami, K ^{[1
]}

机构：

[1] Natl Inst Genet, Div Mol & Dev Biol, Mishima, Shizuoka 4118540, Japan

来源：

DEVELOPMENTAL DYNAMICS | 2005年 / 234卷 / 02期

关键词：

zebrafish; transposon; gene trapping; enhancer trapping; insertional mutagenesis;

D O I：

10.1002/dvdy.20516

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

Zebrafish is an excellent model animal to study vertebrate development by genetic approaches. Hundreds of mutations affecting various processes of development have been isolated by chemical mutagenesis and insertional mutagenesis using a pseudotyped retrovirus. However, useful transposon tools and methods had not been available in zebrafish. This is mainly because no active transposable element has been found from the zebrafish genome. Recently, efficient transgenesis, gene trap, and enhancer trap methods have been developed in zebrafish by using the Toll and the Sleeping Beauty transposon systems. These methods should increase the usefulness of zebrafish as a model vertebrate and facilitate the study of developmental biology, genetics, and genomics.

引用

页码：244 / 254

页数：11

共 79 条

[51] Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage [J].

Kawakami, K ;

Shima, A ;

Kawakami, N .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (21) :11403-11408

[52] The Tomita collection of medaka pigmentation mutants as a resource for understanding neural crest cell development [J].

Kelsh, RN ;

Inoue, C ;

Momoi, A ;

Kondoh, H ;

Furutani-Seiki, M ;

Ozato, K ;

Wakamatsu, Y .

MECHANISMS OF DEVELOPMENT, 2004, 121 (7-8) :841-859

[53] The homeobox protein Six3 interacts with the Groucho corepressor and acts as a transcriptional repressor in eye and forebrain formation [J].

Kobayashi, M ;

Nishikawa, K ;

Suzuki, T ;

Yamamoto, M .

DEVELOPMENTAL BIOLOGY, 2001, 232 (02) :315-326

[54]

Koga A, 2000, GENETICS, V155, P273

[55] Homogeneity in the structure of the medaka fish transposable element Tol2 [J].

Koga, A ;

Hori, H .

GENETICAL RESEARCH, 1999, 73 (01) :7-14

[56] Transposable element in fish [J].

Koga, A ;

Suzuki, M ;

Inagaki, H ;

Bessho, Y ;

Hori, H .

NATURE, 1996, 383 (6595) :30-30

[57] Active transposition in zebrafish [J].

Lam, WL ;

Lee, TS ;

Gilbert, W .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (20) :10870-10875

[58] LACZ EXPRESSION IN GERMLINE TRANSGENIC ZEBRAFISH CAN BE DETECTED IN LIVING EMBRYOS [J].

LIN, S ;

YANG, S ;

HOPKINS, N .

DEVELOPMENTAL BIOLOGY, 1994, 161 (01) :77-83

[59] INTEGRATION AND GERM-LINE TRANSMISSION OF A PSEUDOTYPED RETROVIRAL VECTOR IN ZEBRAFISH [J].

LIN, S ;

GAIANO, N ;

CULP, P ;

BURNS, JC ;

FRIEDMANN, T ;

YEE, JK ;

HOPKINS, N .

SCIENCE, 1994, 265 (5172) :666-669

[60] Transgene expression in zebrafish: A comparison of retroviral-vector and DNA-injection approaches [J].

Linney, E ;

Hardison, NL ;

Lonze, BE ;

Lyons, S ;

DiNapoli, L .

DEVELOPMENTAL BIOLOGY, 1999, 213 (01) :207-216

← 1 2 3 4 5 6 7 8 →