Genome sequences and evolutionary biology, a two-way interaction

被引:25
作者
Charlesworth, D
Charlesworth, B
McVean, GAT
机构
[1] Univ Edinburgh, Inst Cell Anim & Populat Biol, Ashworth Lab, Edinburgh EH9 3JT, Midlothian, Scotland
[2] Univ Oxford, Dept Stat, Oxford OX1 3TG, England
关键词
D O I
10.1016/S0169-5347(01)02126-7
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071012 ; 0713 ;
摘要
Complete genome sequences are accumulating rapidly, culminating with the announcement of the human genome sequence in February 2001. In addition to cataloguing the diversity of genes and other sequences, genome sequences will provide the first detailed and complete data on gene families and genome organization, including data on evolutionary changes. Reciprocally, evolutionary biology will make important contributions to the efforts to understand functions of genes and other sequences in genomes. Large-scale, detailed and unbiased comparisons between species will illuminate the evolution of genes and genomes, and population genetics methods will enable detection of functionally important genes or sequences, including sequences that have been involved in adaptive changes.
引用
收藏
页码:235 / 242
页数:8
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