Consecutive vinylic to aryl to allylic palladium migration and multiple C-H activation processes

被引：78

作者：

Zhao, J

Campo, M

Larock, RC ^{[1
]}

机构：

[1] Iowa State Univ, Dept Chem, Ames, IA 50011 USA

[2] Univ Geneva, Lab Pharm Galen Biopharm, Pharm Sect, CH-1211 Geneva, Switzerland

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 12期

关键词：

C-H activation; deuterium; palladium; rearrangement; synthetic methods;

D O I：

10.1002/anie.200462327

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) "Through-space" migration of palladium between remote carbon atoms appears to take place in the generation of π-allyl-palladium complexes, which are useful intermediates in organic synthesis. The reaction of halogenated arenes with alkynes under Pd-migration conditions provides the mixture of allylic esters A-C (see reaction shown; X = Br, I; R1 = H, OMe, CO2Et, Cl; R2 = Ph, tBu). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1873 / 1875

页数：3

共 26 条

[1] 1,4-Palladium migration via C-H activation, followed by arylation: Synthesis of fused polycycles [J].