X-Ray crystallographic signature of supramolecular triple helix formation from a water soluble synthetic tetrapeptide

被引：23

作者：

Das, AK

Haldar, D

Hegde, RP

Shamala, N ^{[1
]}

Banerjee, A

机构：

[1] Indian Inst Sci, Dept Phys, Bangalore 560012, Karnataka, India

[2] Indian Assoc Cultivat Sci, Dept Biol Chem, Kolkata 700032, W Bengal, India

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 14期

关键词：

D O I：

10.1039/b417726f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Single crystal X-ray diffraction studies on the water soluble, synthetic tetrapeptide Tyr(1)-Aib(2)-Tyr(3)-Val(4) 1 with a non-coded amino acid residue (Aib: alpha-amino isobutyric acid) reveal that the peptide adopts an "S''-shaped molecular structure which self-assembles to form a supramolecular triple helix using various non-covalent interactions including water mediated hydrogen bonds in the solid state.

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页码：1836 / 1838

页数：3

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