Secrets of actin-based motility revealed by a bacterial pathogen

被引：132

作者：

Cameron, LA ^{[1
]}

Giardini, PA ^{[1
]}

Soo, FS ^{[1
]}

Theriot, JA ^{[1
]}

机构：

[1] Stanford Univ, Dept Biochem, Sch Med, Stanford, CA 94305 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2000年 / 1卷 / 02期

关键词：

D O I：

10.1038/35040061

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Actin-based cell motility is a complex process involving a dynamic, self-organizing cellular system. Experimental problems initially limited our understanding of this type of motility, but the use of a model system derived from a bacterial pathogen has led to a breakthrough. Now, all the molecular components necessary for dynamic actin self-organization and motility have been identified, setting the stage for future mechanistic studies.

引用

页码：110 / 119

页数：10

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