Secrets of actin-based motility revealed by a bacterial pathogen

被引：132

作者：

Cameron, LA ^{[1
]}

Giardini, PA ^{[1
]}

Soo, FS ^{[1
]}

Theriot, JA ^{[1
]}

机构：

[1] Stanford Univ, Dept Biochem, Sch Med, Stanford, CA 94305 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2000年 / 1卷 / 02期

关键词：

D O I：

10.1038/35040061

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Actin-based cell motility is a complex process involving a dynamic, self-organizing cellular system. Experimental problems initially limited our understanding of this type of motility, but the use of a model system derived from a bacterial pathogen has led to a breakthrough. Now, all the molecular components necessary for dynamic actin self-organization and motility have been identified, setting the stage for future mechanistic studies.

引用

页码：110 / 119

页数：10

共 99 条

[71] Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3 [J].

Rozelle, AL ;

Machesky, LM ;

Yamamoto, M ;

Driessens, MHE ;

Insall, RH ;

Roth, MG ;

Luby-Phelps, K ;

Marriott, G ;

Hall, A ;

Yin, HL .

CURRENT BIOLOGY, 2000, 10 (06) :311-320

[72] HOST-CELL ACTIN ASSEMBLY IS NECESSARY AND LIKELY TO PROVIDE THE PROPULSIVE FORCE FOR INTRACELLULAR MOVEMENT OF LISTERIA-MONOCYTOGENES [J].

SANGER, JM ;

SANGER, JW ;

SOUTHWICK, FS .

INFECTION AND IMMUNITY, 1992, 60 (09) :3609-3619

[73] LOCALIZATION OF CAPPING PROTEIN IN CHICKEN EPITHELIAL-CELLS BY IMMUNOFLUORESCENCE AND BIOCHEMICAL FRACTIONATION [J].

SCHAFER, DA ;

MOOSEKER, MS ;

COOPER, JA .

JOURNAL OF CELL BIOLOGY, 1992, 118 (02) :335-346

[74] DIACYLGLYCEROL-STIMULATED FORMATION OF ACTIN NUCLEATION SITES AT PLASMA-MEMBRANES [J].

SHARIFF, A ;

LUNA, EJ .

SCIENCE, 1992, 256 (5054) :245-247

[75] Three regions within ActA promote Arp2/3 complex-mediated actin nucleation and Listeria monocytogenes motility [J].

Skoble, J ;

Portnoy, DA ;

Welch, MD .

JOURNAL OF CELL BIOLOGY, 2000, 150 (03) :527-537

[76] ASYMMETRIC DISTRIBUTION OF THE LISTERIA-MONOCYTOGENES ACTA PROTEIN IS REQUIRED AND SUFFICIENT TO DIRECT ACTIN-BASED MOTILITY [J].

SMITH, GA ;

PORTNOY, DA ;

THERIOT, JA .

MOLECULAR MICROBIOLOGY, 1995, 17 (05) :945-951

[77] The tandem repeat domain in the Listeria monocytogenes ActA protein controls the rate of actin-based motility, the percentage of moving bacteria, and the localization of vasodilator-stimulated phosphoprotein and profilin [J].

Smith, GA ;

Theriot, JA ;

Portnoy, DA .

JOURNAL OF CELL BIOLOGY, 1996, 135 (03) :647-660

[78] Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri [J].

Suzuki, T ;

Miki, H ;

Takenawa, T ;

Sasakawa, C .

EMBO JOURNAL, 1998, 17 (10) :2767-2776

[79] Arp2/3 complex and actin depolymerizing factor cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia [J].

Svitkina, TM ;

Borisy, GG .

JOURNAL OF CELL BIOLOGY, 1999, 145 (05) :1009-1026

[80] Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization [J].

Symons, M ;

Derry, JMJ ;

Karlak, B ;

Jiang, S ;

Lemahieu, V ;

McCormick, F ;

Francke, U ;

Abo, A .

CELL, 1996, 84 (05) :723-734

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