Molecular modelling of a template substitute and monomers used in molecular imprinting for aflatoxin B1 micro-HPLC analysis

被引:37
作者
Wyszomirski, Miroslaw [1 ]
Prus, Wojciech [1 ]
机构
[1] Univ Bielsko Biala, PL-43309 Bielsko Biala, Poland
关键词
aflatoxin B1; molecular imprinting; substitute; molecular modelling; POLYMERS; RECOGNITION;
D O I
10.1080/08927022.2012.667876
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070305 [高分子化学与物理];
摘要
The preparation of molecularly imprinted polymers (MIPs) involves the polymerisation of functional monomers in the presence of template molecules. 5,7-Dimethoxycoumarin (DMC) was found to be a structural analogue for aflatoxin B1 (AB1) and serves as its substitute in a grafting solution for the MIP synthesis. It was found that both methacrylic acid and allylamine are functional monomers which could provide a similar binding towards AB1 and DMC.
引用
收藏
页码:892 / 895
页数:4
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