Phosphatase protein homologue to tensin expression and phosphatidylinositol-3 phosphate kinase mutations in colorectal cancer

被引:44
作者
Frattini, M [1 ]
Signoroni, S
Pilotti, S
Bertario, L
Benvenuti, S
Zanon, C
Bardelli, A
Pierotti, MA
机构
[1] Ist Nazl Studio Cura Tumori, Dept Pathol, Unit Expt Mol Pathol, Milan, Italy
[2] Ist Nazl Studio Cura Tumori, Unit Predict Prevent Med, Milan, Italy
[3] Univ Turin, Sch Med, Oncogenom Ctr, Inst Canc Res & Treatment, Turin, Italy
[4] FDn Italiana Ric Canc, Inst Mol Oncol, Milan, Italy
[5] Ist Nazl Studio Cura Tumori, Dept Expt Oncol, Milan, Italy
关键词
D O I
10.1158/0008-5472.CAN-05-2780
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:11227 / 11227
页数:1
相关论文
共 5 条
[1]   Different genetic features associated with colon and rectal carcinogenesis [J].
Frattini, M ;
Balestra, D ;
Suardi, S ;
Oggionni, M ;
Alberici, P ;
Radice, P ;
Costa, A ;
Daidone, MG ;
Leo, E ;
Pilotti, S ;
Bertario, L ;
Pierotti, MA .
CLINICAL CANCER RESEARCH, 2004, 10 (12) :4015-4021
[2]   PI3K-Akt pathway: Its functions and alterations in human cancer [J].
Osaki, M ;
Oshimura, M ;
Ito, H .
APOPTOSIS, 2004, 9 (06) :667-676
[3]   Colorectal cancer - Mutations in a signalling pathway [J].
Parsons, DW ;
Wang, TL ;
Samuels, Y ;
Bardelli, A ;
Cummins, JM ;
DeLong, L ;
Silliman, N ;
Ptak, J ;
Szabo, S ;
Willson, JKV ;
Markowitz, S ;
Kinzler, K ;
Vogelstein, B ;
Lengauer, C ;
Velculescu, VE .
NATURE, 2005, 436 (7052) :792-792
[4]   PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma [J].
Saal, LH ;
Holm, K ;
Maurer, M ;
Memeo, L ;
Su, T ;
Wang, XM ;
Yu, JS ;
Malmström, PO ;
Mansukhani, M ;
Enoksson, J ;
Hibshoosh, H ;
Borg, Å ;
Parsons, R .
CANCER RESEARCH, 2005, 65 (07) :2554-2559
[5]   High frequency of mutations of the PIK3CA gene in human cancers [J].
Samuels, Y ;
Wang, ZH ;
Bardelli, A ;
Silliman, N ;
Ptak, J ;
Szabo, S ;
Yan, H ;
Gazdar, A ;
Powell, DM ;
Riggins, GJ ;
Willson, JKV ;
Markowitz, S ;
Kinzler, KW ;
Vogelstein, B ;
Velculescu, VE .
SCIENCE, 2004, 304 (5670) :554-554