Biomimetic glass nanopores employing aptamer gates responsive to a small molecule

被引：42

作者：

Abelow, Alexis E. ^{[3
]}

Schepelina, Olga ^{[3
]}

White, Ryan J. ^{[1
,2
]}

Vallee-Belisle, Alexis ^{[1
,2
]}

Plaxco, Kevin W. ^{[1
,2
]}

Zharov, Ilya ^{[3
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

[2] Univ Calif Santa Barbara, Program Biomol Sci & Engn, Santa Barbara, CA 93106 USA

[3] Univ Utah, Dept Chem, Salt Lake City, UT 84112 USA

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 42期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

SOLID-STATE NANOPORES; IONIC TRANSPORT; POLYMER BRUSHES; SURFACE-CHARGE; DNA; ELECTRODE; COCAINE; SENSOR; SELECTION; CHANNELS;

D O I：

10.1039/c0cc02649b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report the preparation of 20 and 65 nm radii glass nanopores whose surface is modified with DNA aptamers controlling the molecular transport through the nanopores in response to small molecule binding.

引用

页码：7984 / 7986

页数：3

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