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Antifungal flavanones and prenylated hydroquinones from Piper crassinervium Kunth

被引：95
作者：
Danelutte, AP
Lago, JHG
Young, MCM
Kato, MJ
机构：
[1] Univ Sao Paulo, Inst Quim, BR-05599970 Sao Paulo, Brazil
[2] Inst Bot, Secao Fisiol & Bioquim Plantas, BR-10051 Sao Paulo, Brazil
来源：
PHYTOCHEMISTRY | 2003年 / 64卷 / 02期
基金：
巴西圣保罗研究基金会;
关键词：
Piper crassinervium; Piperaceae; prenylated hydroquinones; flavanones; antifungal activity;
D O I：
10.1016/S0031-9422(03)00299-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bioactivity-guided fractionation of the EtOAc extract from leaves of Piper crassinervium yielded three prenylated hydroquinones together with two known flavanones naringenin and sakuranetin. Their structures were determined by means of spectroscopic analysis (NMR, IR, UV and MS) including two-dimensional NMR spectroscopy experiments (H-1-H-1 COSY, HMQC, HMBC and NOESY). The antifungal activity was determined by direct bioautography against Cladosporium cladosporioides and C. sphaerospermum. (C) 2003 Elsevier Ltd. All rights reserved.
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收藏
页码：555 / 559
页数：5
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