NDM-1, OXA-48 and OXA-181 carbapenemase-producing Enterobacteriaceae in Sultanate of Oman

被引：98

作者：

Dortet, L. ^{[1
]}

Poirel, L. ^{[1
]}

Al Yaqoubi, F. ^{[2
]}

Nordmann, P. ^{[1
]}

机构：

[1] Hop Bicetre, AP HP, INSERM Emerging Resistance Antibiot U914, Serv Bacteriol Virol,Fac Med Paris Sud, F-94275 Le Kremlin Bicetre, France

[2] Royal Hosp, Dept Microbiol, Muscat, Oman

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2012年 / 18卷 / 05期

关键词：

Carbapenemase; gram-negative; NDM-1; OXA-181; OXA-48; EMERGENCE; IDENTIFICATION; RESISTANCE;

D O I：

10.1111/j.1469-0691.2012.03796.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Twenty-two carbapenem-resistant enterobacterial isolates were recovered from patients hospitalized between October 2010 and March 2011 at the Royal Hospital of Muscat, Sultanate of Oman. Eleven NDM-1, five OXA-48 and one NDM-1 plus OXA-181 producers of diverse ST types were recovered from clinical samples. All carbapenemase genes were located on self-conjugative plasmids and were nearly always associated with other resistance determinants, including extended-spectrum beta-lactamases and the ArmA methylase encoding resistance to aminoglycosides. This work highlights the dissemination of NDM-1 and OXA-48-type producers in the Middle East.

引用

页码：E144 / E148

页数：5

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