Organocatalytic transformation of 1,3-diketones into optically active cyclohexanones

被引：46

作者：

Gryko, D ^{[1
]}

机构：

[1] Polish Acad Sci, Inst Organ Chem, PL-01224 Warsaw, Poland

来源：

TETRAHEDRON-ASYMMETRY | 2005年 / 16卷 / 07期

关键词：

D O I：

10.1016/j.tetasy.2005.02.005

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The domino Michael-aldol reaction of 1,3-diketones with MVK in the presence of L-proline furnished highly substituted cyclohexanones in a regio- and stereocontrolled manner. When the reaction was performed in NMP, high yields (up to 93%) and enantioselectivities up to 80% were observed. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1377 / 1383

页数：7

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