A Remote Biosensor Platform Using Sputtered Magnetostrictive Particles

被引：44

作者：

Johnson, M. L. ^{[1
]}

Hu, J. ^{[1
]}

Wan, J. ^{[1
]}

Lakshmanan, R. S. ^{[1
]}

Petrenko, V. A. ^{[2
]}

Chin, B. A. ^{[1
]}

机构：

[1] Auburn Univ, Dept Mech Engn, Mat Res & Educ Ctr, Auburn, AL 36849 USA

[2] Auburn Univ, Coll Vet Med, Dept Pathol, Auburn, AL 36849 USA

来源：

PROCESSING AND FABRICATION OF ADVANCED MATERIALS XV | 2006年

关键词：

magnetostriction; biosensor; iron; boron; sputtering; bacteriophage;

D O I：

10.1007/7089_051

中图分类号：

TH [机械、仪表工业];

学科分类号：

0802 ;

摘要：

A wireless biosensor has been developed using magnetostrictive particles with a composition of Fe79B21 and largest dimension on the order of 10(2) microns. Upon the application of an external magnetic field, these particles will exhibit a characteristic resonance frequency, determined by their size and mass, due to the phenomena of magnetostriction. The particles are produced using the microelectronic fabrication techniques of photolithography and physical vapor deposition. The biosensor is formed by coating the magnetostrictive particle with a thin layer of gold (for environmental stability as well as bioactivity) and immobilizing a biomolecular recognition element (e.g. bacteriophage) on the surfaces. Once the targeted antigen (e.g. Bacillus anthracis, anthrax spores, or Salmonella bacteria) comes in contact with the biosensor, the bacteriophage will bind with the antigen, thereby increasing the particle's mass and causing a shift in the resonance frequency.

引用

页码：223 / +

页数：3

共 19 条

[1]

[Anonymous], THEORY ELASTICITY

[2] MOSSBAUER INVESTIGATION OF SPUTTERED FERROMAGNETIC AMORPHOUS FEXB100-X FILMS [J].

BLUM, NA ;

MOORJANI, K ;

POEHLER, TO ;

SATKIEWICZ, FG .

JOURNAL OF APPLIED PHYSICS, 1982, 53 (03) :2074-2076

[3] Diagnostic probes for Bacillus anthracis spores selected from a landscape phage library [J].

Brigati, J ;

Williams, DD ;

Sorokulova, IB ;

Nanduri, V ;

Chen, IH ;

Turnbough, CL ;

Petrenko, VA .

CLINICAL CHEMISTRY, 2004, 50 (10) :1899-1906

[4] Magnetostrictive thin films prepared by RF sputtering [J].

Carabias, I ;

Martinez, A ;

Garcia, MA ;

Pina, E ;

Gonzalez, JM ;

Hernando, A ;

Crespo, P .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2005, 290 (290-291 PART 2) :823-825

[5]

CHIN BA, 2005, Patent No. 20050074904

[6] MAGNETIC AND STRUCTURAL-PROPERTIES OF FE-B BINARY METALLIC GLASSES .1. VARIATION OF MAGNETIC-MOMENT WITH COMPOSITION [J].

COWLAM, N ;

CARR, GE .

JOURNAL OF PHYSICS F-METAL PHYSICS, 1985, 15 (05) :1109-1116

[7]

DELACHEISSERIE ED, 1993, MAGNETOSTRICTION THE, pCH3

[8] SOFT MAGNETIC-MATERIALS [J].

FISH, GE .

PROCEEDINGS OF THE IEEE, 1990, 78 (06) :947-972

[9] MAGNETOELASTIC WAVE EXCITATION PROPERTIES OF AMORPHOUS IRON-BORON FILMS PREPARED BY RF-HIGH RATE SPUTTERING [J].

FUJII, T ;

KUMURA, T ;

MIYAMA, T ;

INOUE, M .

JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS SHORT NOTES & REVIEW PAPERS, 1983, 22 (01) :79-87

[10] Magnetoelastic sensors for remote query environmental monitoring [J].

Grimes, CA ;

Ong, KG ;

Loiselle, K ;

Stoyanov, PG ;

Kouzoudis, D ;

Liu, Y ;

Tong, C ;

Tefiku, F .

SMART MATERIALS & STRUCTURES, 1999, 8 (05) :639-646

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