Parallel, double-helix DNA nanostructures using interstrand cross-linked oligonucleotides with bismaleimide linkers

被引:19
作者
Endo, M [1 ]
Majima, T [1 ]
机构
[1] Osaka Univ, Inst Sci & Ind Res, Osaka 5670047, Japan
关键词
DNA structures; DNA; molecular assembly; nanostructures; supramolecular chemistry;
D O I
10.1002/anie.200352546
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Micrometer-scale rodlike DNA architectures can be synthesized by one-step molecular assembly using cross-linked oligonucleotides with bismaleimide linkers and subsequent DNA ligation (see scheme). Atomic force microscopy studies have shown that the flexibility of the DNA structures in the parallel double-helix structure is reduced.
引用
收藏
页码:5744 / 5747
页数:4
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