Synthesis and biological activity of some new pyrazoline and pyrrolo[3,4-c]pyrazole-4,6-dione derivatives: Reaction of nitrilimines with some dipolarophiles

被引：41

作者：

Abunada, Nada M. ^{[1
]}

Hassaneen, Hamdi M. ^{[2
]}

Kandile, Nadia G. ^{[3
]}

Miqdad, Omar A. ^{[1
]}

机构：

[1] Al Aqsa Univ, Dept Chem, Fac Sci Appl, Gaza, Israel

[2] Cairo Univ, Dept Chem, Fac Sci, Cairo, Egypt

[3] Ain Shams Univ, Dept Chem, Univ Coll Women, Cairo, Egypt

来源：

MOLECULES | 2008年 / 13卷 / 04期

关键词：

pyrazoline; pyrrolo[3,4-c]pyrazole-4,6-dione; nitrilimine; dipolarophile; biological activity;

D O I：

10.3390/molecules13041011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Several 1,3-diaryl-5-(cyano-, aminocarbonyl- and ethoxycarbonyl-)-2-pyrazoline, pyrrolo[3,4-c] pyrazole-4,6-dione and 1,3,4,5-tetraaryl-2-pyrazoline derivatives were prepared by the reaction of nitrilimine with different dipolarophilic reagents. The new compounds were characterized using IR, H-1-NMR, C-13-NMR and mass spectra. Biological screening of some compounds is reported.

引用

页码：1011 / 1024

页数：14

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