Intracellular enzymatic formation of nanofibers results in hydrogelation and regulated cell death

被引：260

作者：

Yang, Zhimou

Xu, Keming

Guo, Zufeng

Guo, Zhihong

Xu, Bing ^{[1
]}

机构：

[1] Hong Kong Univ Sci & Technol, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[2] Hong Kong Univ Sci & Technol, Bioengn Program, Hong Kong, Hong Kong, Peoples R China

来源：

ADVANCED MATERIALS | 2007年 / 19卷 / 20期

关键词：

D O I：

10.1002/adma.200701971

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Enzymatic formation of supramolecular nanofibers is demonstrated as a novel approach to induce intracellular hydrogelation and control the fate of cells or cellular functions, which can lead to a new paradigm for developing biomaterials to manage cellular artificial nanostructures (CAN), understand cellular functions beyond the molecular level, and create novel therapeutics.

引用

收藏

页码：3152 / +

页数：6

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