Decision-making dysfunctions in psychiatry - Altered homeostatic processing?

被引:230
作者
Paulus, Martin P.
机构
[1] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92037 USA
[2] Vet Affairs Hlth Care Syst San Diego, La Jolla, CA 92161 USA
关键词
D O I
10.1126/science.1142997
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Decision-making consists of selecting an action from a set of available options. This results in an outcome that changes the state of the decision-maker. Therefore, decision-making is part of a homeostatic process. Individuals with psychiatric disorders show altered decision-making. They select options that are either non-optimal or nonhomeostatic. These dysfunctional patterns of decision-making in individuals with psychiatric disorders may fundamentally relate to problems with homeostatic regulation. These may manifest themselves in (i) how the length of time between decisions and their outcomes influences subsequent decision-making, (ii) how gain and loss feedback are integrated to determine the optimal decision, (iii) how individuals adapt their decision strategies to match the specific context, or (iv) how seemingly maladaptive responses result from an attempt to establish an unstable homeostatic balance.
引用
收藏
页码:602 / 606
页数:5
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