Imatinib mesylate in combination with chemotherapy in four children with de novo and advanced stage Philadelphia chromosome-positive acute lymphoblastic leukemia

被引：14

作者：

Luis Fuster, Jose ^{[1
]}

Bermudez, Mar ^{[1
]}

Galera, Ana ^{[1
]}

Esther Llinares, Maria ^{[1
]}

Calle, Doris ^{[2
]}

Jose Ortuno, Francisco ^{[3
]}

机构：

[1] Hosp Univ Virgen Arrixaca, Murcia, Spain

[2] Clin Solca, Guayaquil, Ecuador

[3] Hosp Morales Meseguer, Murcia, Spain

来源：

HAEMATOLOGICA | 2007年 / 92卷 / 12期

关键词：

Philadelphia chromosome; ALL; childhood; imatinib; chemotherapy;

D O I：

10.3324/haematol.11525

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The role of imatinib in childhood Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) has not been established. We treated four children with imatinib in combination with conventional chemotherapy (CT) before stem cell transplantation (SCT). Response evaluation consisted of fluorocytometric analysis of minimal residual disease (MRD) and standard qualitative RT-PCR follow-up.

引用

页码：1723 / 1724

页数：2

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