Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

被引：898

作者：

Chen, Xiaoqiang ^{[2
,3
,4
]}

Tian, Xizhe ^{[1
]}

Shin, Injae ^{[1
]}

Yoon, Juyoung ^{[2
,3
]}

机构：

[1] Yonsei Univ, Dept Chem, Ctr Biofunct Mol, Seoul 120749, South Korea

[2] Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 120750, South Korea

[3] Ewha Womans Univ, Dept Bioinspired Sci WCU, Seoul 120750, South Korea

[4] Nanjing Univ Technol, State Key Lab Mat Oriented Chem Engn, Coll Chem & Chem Engn, Nanjing 210009, Peoples R China

来源：

CHEMICAL SOCIETY REVIEWS | 2011年 / 40卷 / 09期

基金：

新加坡国家研究基金会;

关键词：

NITRIC-OXIDE DETECTION; FLOW-INJECTION SPECTROFLUOROMETRY; SUPEROXIDE ANION-RADICALS; IMAGING HYDROGEN-PEROXIDE; LIVING CELLS; SINGLET-OXYGEN; HYDROXYL RADICALS; IN-VIVO; RATIONAL DESIGN; SELECTIVE DETECTION;

D O I：

10.1039/c1cs15037e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Oxidative and nitrosative stress induced by ROS/RNS play crucial roles in a wide range of physiological processes and are also implicated in various diseases, including cancer and neurodegenerative disorders. Sensitive and selective methods for the detection of ROS/RNS based on fluorescent and luminescent probes are of great use in monitoring the in vivo production of these species and elucidating their biological functions. This critical review highlights recent advances that have been made in the development of fluorescent and luminescent probes employed to monitor various ROS/RNS (132 references).

引用

页码：4783 / 4804

页数：22

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