Chronic myeloid leukemia with a rare variant Philadelphia translocation: t(9;10;22)(q34;q22;q11)

被引：8

作者：

Emberger, W

Behmel, A

Tschernigg, M

Seewann, HL

Petek, E

Kroisel, PM

Wagner, K

机构：

[1] Graz Univ, Inst Med Biol & Human Genet, A-8010 Graz, Austria

[2] Landeskrankenhaus Furstenfeld, Dept Hematol, A-8280 Furstenfeld, Austria

来源：

CANCER GENETICS AND CYTOGENETICS | 2001年 / 129卷 / 01期

关键词：

D O I：

10.1016/S0165-4608(01)00417-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report a 59-year-old, male, chronic myeloid leukemia patient with a rare variant Philadelphia (Ph) translocation t(9;10;22)(q34;q22;q11). Fluorescence in situ hybridization with whole chromosome paints was used to confirm the cytogenetic findings. With a BCR/ABL-specific probe. the known rearrangement on the derivative chromosome 22 was found. The prognostic implications as well as the relevance of the additional breakpoint region 10q22 are discussed. (C) 2001 Elsevier Science Inc. All rights reserved.

引用

页码：76 / 79

页数：4

共 36 条

[31] Fluorescence in situ hybridization provides evidence for two-step rearrangement in a masked Ph chromosome formation [J].