Leveraging models of cell regulation and GWAS data in integrative network-based association studies

被引：187

作者：

Califano, Andrea ^{[1
,2
,3
]}

Butte, Atul J. ^{[4
,5
]}

Friend, Stephen ^{[6
]}

Ideker, Trey ^{[7
,8
,9
]}

Schadt, Eric ^{[10
]}

机构：

[1] Columbia Univ, Columbia Initiat Syst Biol, New York, NY 10027 USA

[2] Columbia Univ, Dept Biochem & Mol Biophys, New York, NY USA

[3] Columbia Univ, Dept Biomed Informat, New York, NY USA

[4] Stanford Univ, Dept Pediat, Sch Med, Stanford, CA 94305 USA

[5] Stanford Univ, Ctr Pediat Bioinformat, Lucile Packard Childrens Hosp, Stanford, CA 94305 USA

[6] Sage Bionetworks, Seattle, WA USA

[7] Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA

[8] Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA

[9] Univ Calif San Diego, Inst Genom Med, La Jolla, CA 92093 USA

[10] Mt Sinai Sch Med, Inst Genom & Multiscale Biol, New York, NY USA

来源：

NATURE GENETICS | 2012年 / 44卷 / 08期

基金：

美国国家卫生研究院;

关键词：

GENOME-WIDE ASSOCIATION; GENE-EXPRESSION; PROTEIN-INTERACTION; MOLECULAR NETWORKS; PREDICTION; PATHWAYS; MAP; PROLIFERATION; PERTURBATION; MECHANISMS;

D O I：

10.1038/ng.2355

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

[No abstract available]

引用

页码：841 / 847

页数：7

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