Novel superparamagnetic core(shell) nanoparticles for magnetic targeted drug delivery and hyperthermia treatment

被引:55
作者
Gangopadhyay, P [1 ]
Gallet, S [1 ]
Franz, E [1 ]
Persoons, A [1 ]
Verbiest, T [1 ]
机构
[1] Catholic Univ Louvain, Dept Chem, Ctr Mol Elect & Photon, B-3001 Heverlee, Belgium
关键词
core(shell) nanoparticles; hyperthermia; maghemite (gold); magnetic targeted drug delivery;
D O I
10.1109/TMAG.2005.854805
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Superparamagnetic gamma-Fe2O3 (Au) core(shell) nanoparticles with narrow size distribution and different shell thicknesses are synthesized. On conjugation with serum albumin, this set of particles forms an ideal candidate to be used in magnetic targeted drug delivery and hyperthermia treatment. In this contribution, the synthesis and characterizations of their size, optical, and magnetic properties are reported. It has also been shown that using different shell thicknesses, it is possible to tune not only the plasmon response of the gold shell but also the magnetic property of these superparamagnetic nanopartieles.
引用
收藏
页码:4194 / 4196
页数:3
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