Genetic Events That Shape the Cancer Epigenome

被引：45

作者：

Ryan, Russell J. H. ^{[1
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,4
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Bernstein, Bradley E. ^{[1
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,4
]}

机构：

[1] Massachusetts Gen Hosp, Howard Hughes Med Inst, Dept Pathol, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Ctr Canc Res, Boston, MA 02114 USA

[3] Harvard Univ, Sch Med, Boston, MA 02114 USA

[4] Broad Inst Harvard & MIT, Cambridge, MA 02142 USA

来源：

SCIENCE | 2012年 / 336卷 / 6088期

关键词：

MUTATIONS; DIFFERENTIATION; EZH2;

D O I：

10.1126/science.1223730

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mutations in chromatin-related genes in human tumors support a role for epigenetic mechanisms in driving cancer.

引用

页码：1513 / 1514

页数：2

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