Total asymmetric synthesis of sperabillins B and D

被引:28
作者
Davies, SG [1 ]
Kelly, RJ [1 ]
Mortimer, AJP [1 ]
机构
[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England
关键词
D O I
10.1039/b305740b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A consise route to the core fragment of sperabillins B and D, methyl (3R, 5R, 6R)-3,6-diamino-5-hydroxyheptanoate, has been developed with a subsequent novel protection strategy allowing the total asymmetric synthesis of sperabillins B and D.
引用
收藏
页码:2132 / 2133
页数:2
相关论文
共 12 条
[1]  
Davies SG, 2002, SYNLETT, P1146
[3]   Asymmetric synthesis of a highly functionalized β-amino acid:: the key amino acid of sperabillins B and D [J].
Davies, SG ;
Ichihara, O .
TETRAHEDRON LETTERS, 1999, 40 (52) :9313-9316
[4]  
GRENOUILLET P, 1987, Patent No. 864644
[5]  
HAMADA M, 1970, J ANTIBIOT, V23, P171
[6]  
HARADA S, 1986, Patent No. 206068
[7]   STEREOSELECTIVE SYNTHESIS OF SPERABILLINS AND RELATED-COMPOUNDS [J].
HASHIGUCHI, S ;
KAWADA, A ;
NATSUGARI, H .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1991, (10) :2435-2444
[8]   STRUCTURES OF NEW PSEUDO-PEPTIDE ANTIBIOTICS, SPERABILLINS [J].
HIDA, T ;
TSUBOTANI, S ;
FUNABASHI, Y ;
ONO, H ;
HARADA, S .
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1993, 66 (03) :863-869
[9]  
HIDA T, 1993, CHEM PHARM BULL, V41, P889
[10]  
HILGETAG G, 1964, CHEM BER, P704