A novel linker for the attachment of alcohols to solid supports

被引:30
作者
Böhm, G [1 ]
Dowden, J [1 ]
Rice, DC [1 ]
Burgess, I [1 ]
Pilard, JF [1 ]
Guilbert, B [1 ]
Haxton, A [1 ]
Hunter, RC [1 ]
Turner, NJ [1 ]
Flitsch, SL [1 ]
机构
[1] Univ Edinburgh, Dept Chem, Edinburgh Ctr Prot Technol, Edinburgh EH9 3JJ, Midlothian, Scotland
基金
英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;
关键词
supported reactions; enzymes; alcohols; carbohydrates;
D O I
10.1016/S0040-4039(98)00593-0
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel linker for the immobilisation of alcohols on solid support is described. This linker can be cleaved either enzymatically using penicillin amidase, or by very mild acid hydrolysis using 10% TFA. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:3819 / 3822
页数:4
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