Fatigue in Parkinson's Disease: Prevalence and Associated Factors

被引：40

作者：

Beiske, Antoine G. ^{[1
]}

Loge, Jon Havard ^{[2
,3
]}

Hjermstad, Marianne J. ^{[4
,5
]}

Svensson, Elisabeth ^{[6
]}

机构：

[1] Akershus Univ Hosp, Dept Neurol, N-1478 Lorenskog, Norway

[2] Oslo Univ Hosp Montebello, Natl Resource Ctr Late Effects, Dept Oncol, Oslo, Norway

[3] Univ Oslo, Dept Behav Sci Med, N-0316 Oslo, Norway

[4] Oslo Univ Hosp, Reg Ctr Excellence Palliat Care, Dept Oncol, Ulleval, Norway

[5] Norwegian Univ Sci & Technol, Fac Med, Dept Canc Res & Mol Med, Trondheim, Norway

[6] Norwegian Inst Publ Hlth, Dept Adult Mental Hlth, Div Mental Hlth, Trondheim, Norway

来源：

MOVEMENT DISORDERS | 2010年 / 25卷 / 14期

关键词：

fatigue; Parkinson; prevalence; Norway; chronic fatigue; associated factors; population based; NONMOTOR SYMPTOMS; PHYSICAL FATIGUE; HEALTH SURVEY; SCALE; SLEEP; QUALITY; SF-36;

D O I：

10.1002/mds.23372

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The purpose of this study was to examine the prevalence of fatigue in Parkinson's disease (PD) patients and compare this to the general population. Factors associated with fatigue were investigated by linear regression. Fatigue was assessed by the fatigue questionnaire. The mean age of the 176 PD patients (41% women) was 69 years (range 35-90), and the mean UPDRSIII was 22.3 (SD 11.7). Fatigue levels (means) were significantly higher in PD patients compared with the general population; however, effect sizes were moderate for women for physical and total fatigue indicating clinically significant differences here only. Only female PD patients had more chronic fatigue than the general population. Fatigue was related to characteristics of PD but also to sleep disturbance, depression, and gender. This population-based study demonstrates that fatigue is a common symptom in PD patients, but compared with the general population, clinically significant differences were only found for female PD patients. (C) 2010 Movement Disorder Society

引用

页码：2456 / 2460

页数：5

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