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Higher-order structure of chromatin and chromosomes

被引：205
作者：
Woodcock, CL [1 ]
Dimitrov, S
机构：
[1] Univ Massachusetts, Inst Biol, Amherst, MA 01003 USA
[2] Inst Albert Bonniot, INSERM, U309, F-38706 Grenoble, France
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 2001年 / 11卷 / 02期
关键词：
D O I：
10.1016/S0959-437X(00)00169-6
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The linear array of nucleosomes that comprises the primary structure of chromatin is folded and condensed to varying degrees in nuclei and chromosomes forming 'higher order structures'. We discuss the recent findings from novel experimental approaches that have yielded significant new information on the different hierarchical levels of chromatin folding and their functional significance.
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页码：130 / 135
页数：6
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