Lineage-specific amino acid substitutions in region 2 of the RNA polymerase σ subunit affect the temperature of promoter opening

被引：4

作者：

Barinova, N. ^{[1
]}

Zhilina, E. ^{[1
]}

Bass, I. ^{[1
]}

Nikiforov, V. ^{[1
,2
]}

Kulbachinskiy, A. ^{[1
]}

机构：

[1] Inst Mol Genet, Lab Mol Genet Microorganisms, Moscow 123182, Russia

[2] Publ Hlth Res Inst, Newark, NJ 07103 USA

来源：

JOURNAL OF BACTERIOLOGY | 2008年 / 190卷 / 08期

关键词：

D O I：

10.1128/JB.00008-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Highly conserved amino acid residues in region 2 of the RNA polymerase or subunit are known to participate in promoter recognition and opening. We demonstrated that nonconserved residues in this region collectively determine lineage-specific differences in the temperature of promoter opening.

引用

页码：3088 / 3092

页数：5

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