Novel estrogen receptor coregulators and signaling molecules in human diseases

被引：38

作者：

Barnes, CJ ^{[1
]}

Vadlamudi, RK ^{[1
]}

Kumar, R ^{[1
]}

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Dept Mol & Cellular Oncol, Houston, TX 77030 USA

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 2004年 / 61卷 / 03期

关键词：

estrogen receptor; coregulators; breast cancer; signaling pathways; chromatin remodeling;

D O I：

10.1007/s00018-003-3222-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The steroid hormone estrogen and signaling from its receptors are increasingly recognized as critical mediators of a variety of organ-specific biological processes. Recent advances in the identification and functional characterization of novel estrogen receptor interacting proteins clearly show the complexity of hormonal signaling regulation, but may also contribute to our understanding of the roles of estrogen signaling in normal physiology and the pathobiology of human disease.

引用

页码：281 / 291

页数：11

共 110 条

[1] Association of steroid receptor coactivator AIB1 with estrogen receptor-α in breast cancer cells [J].

Azorsa, DO ;

Cunliffe, HE ;

Meltzer, PS .

BREAST CANCER RESEARCH AND TREATMENT, 2001, 70 (02) :89-101

[2] Functional interactions between the estrogen receptor coactivator PELP1/MNAR and retinoblastoma protein [J].

Balasenthil, S ;

Vadlamudi, RK .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (24) :22119-22127

[3]

Bautista S, 1998, CLIN CANCER RES, V4, P2925

[4] Oestrogen as a neuroprotective hormone [J].

Behl, C .

NATURE REVIEWS NEUROSCIENCE, 2002, 3 (06) :433-442

[5] ROLE OF THE 2 ACTIVATING DOMAINS OF THE ESTROGEN-RECEPTOR IN THE CELL-TYPE AND PROMOTER-CONTEXT DEPENDENT AGONISTIC ACTIVITY OF THE ANTIESTROGEN 4-HYDROXYTAMOXIFEN [J].

BERRY, M ;

METZGER, D ;

CHAMBON, P .

EMBO JOURNAL, 1990, 9 (09) :2811-2818

[6] The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription [J].

Brunnberg, S ;

Pettersson, K ;

Rydin, E ;

Matthews, J ;

Hanberg, A ;

Pongratz, I .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (11) :6517-6522

[7] NUCLEAR FACTOR RIP140 MODULATES TRANSCRIPTIONAL ACTIVATION BY THE ESTROGEN-RECEPTOR [J].

CAVAILLES, V ;

DAUVOIS, S ;

LHORSET, F ;

LOPEZ, G ;

HOARE, S ;

KUSHNER, PJ ;

PARKER, MG .

EMBO JOURNAL, 1995, 14 (15) :3741-3751

[8] Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-α [J].

Cenci, S ;

Weitzmann, MN ;

Roggia, C ;

Namba, N ;

Novack, D ;

Woodring, J ;

Pacifici, R .

JOURNAL OF CLINICAL INVESTIGATION, 2000, 106 (10) :1229-1237

[9] M-CSF neutralization and Egr-1 deficiency prevent ovariectomy-induced bone loss [J].

Cenci, S ;

Weitzmann, MN ;

Gentile, MA ;

Aisa, MC ;

Pacifici, R .

JOURNAL OF CLINICAL INVESTIGATION, 2000, 105 (09) :1279-1287

[10] Effects of raloxifene on carotid blood flow resistance and endothelium-dependent vasodilation in postmenopausal women [J].

Ceresini, G ;

Marchini, L ;

Rebecchi, I ;

Morganti, S ;

Bertone, L ;

Montanari, I ;

Bacchi-Modena, A ;

Sgarabotto, M ;

Baldini, M ;

Denti, L ;

Ablondi, F ;

Ceda, GP ;

Valenti, G .

ATHEROSCLEROSIS, 2003, 167 (01) :121-127

← 1 2 3 4 5 6 7 8 9 10 →