Novel estrogen receptor coregulators and signaling molecules in human diseases

被引：38

作者：

Barnes, CJ ^{[1
]}

Vadlamudi, RK ^{[1
]}

Kumar, R ^{[1
]}

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Dept Mol & Cellular Oncol, Houston, TX 77030 USA

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 2004年 / 61卷 / 03期

关键词：

estrogen receptor; coregulators; breast cancer; signaling pathways; chromatin remodeling;

D O I：

10.1007/s00018-003-3222-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The steroid hormone estrogen and signaling from its receptors are increasingly recognized as critical mediators of a variety of organ-specific biological processes. Recent advances in the identification and functional characterization of novel estrogen receptor interacting proteins clearly show the complexity of hormonal signaling regulation, but may also contribute to our understanding of the roles of estrogen signaling in normal physiology and the pathobiology of human disease.

引用

页码：281 / 291

页数：11

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