Palladium-catalyzed highly regio- and stereoselective addition of organoboronic acids to allenes in the presence of AcOH

被引：52

作者：

Ma, SM

Jiao, N

Ye, LW

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2003年 / 9卷 / 24期

关键词：

alkenes; allenes organoboronic acids; palladium;

D O I：

10.1002/chem.200305301

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Pd-0-catalyzed regio- and stereoselective addition of organoboronic acids to allenes leads to stereodefined tri- or tetrasubstituted alkenes. Furthermore, this method shows high substitutent-loading capability and tolerance of various substitutents. A hydropalladation-Suzuki coupling mechanism, which may account for the regio- and stereoselectivity, is proposed.

引用

页码：6049 / 6056

页数：8

共 74 条

[1] SYNTHESIS OF 2,2,4-TRIPHENYL-3-PROPENOYL-3,4-DIHYDRO-2H-BENZOPYRAN VIA A LITHIATED ALLENE [J].