Nanostructures for Medical Diagnostics

被引:29
作者
Bellah, Md. Motasim [1 ,2 ]
Christensen, ShawnM. [3 ]
Iqbal, Samir M. [1 ,2 ,4 ,5 ]
机构
[1] Univ Texas Arlington, Dept Elect Engn, Arlington, TX 76011 USA
[2] Univ Texas Arlington, Nanotechnol Res & Teaching Facil, Arlington, TX 76019 USA
[3] Univ Texas Arlington, Dept Biol, Arlington, TX 76010 USA
[4] Univ Texas Arlington, Joint Grad Comm Bioengn Program, Arlington, TX 76010 USA
[5] Univ Texas Arlington, Dept Bioengn, Arlington, TX 76010 USA
关键词
LABEL-FREE DETECTION; ELECTRICAL DETECTION; BOTTOM-UP; IN-VITRO; ULTRAFINE PARTICLES; SELECTIVE DETECTION; GOLD NANOPARTICLES; CARBON NANOTUBES; DNA-SEQUENCE; NANOTECHNOLOGY;
D O I
10.1155/2012/486301
中图分类号
TB3 [工程材料学];
学科分类号
082905 [生物质能源与材料];
摘要
Nanotechnology is the art of manipulating materials on atomic or molecular scales especially to build nanoscale structures and devices. The field is expanding quickly, and a lot of work is ongoing in the design, characterization, synthesis, and application of materials, structures, devices, and systems by controlling shape and size at nanometer scale. In the last few years, much work has been focused on the use of nanostructures toward problems of biology and medicine. In this paper, we focus on the application of various nanostructures and nanodevices in clinical diagnostics and detection of important biological molecules. The discussion starts by introducing some basic techniques ofmicro-/nanoscale fabrication that have enabled reproducible production of nanostructures. The prospects, benefits, and limitations of using these novel techniques in the fields of biodetection and medical diagnostics are then discussed. Finally, the challenges of mass production and acceptance of nanotechnology by the medical community are considered.
引用
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页数:21
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