Stereoinversion of β- and γ-substituted α-amino acids using a chemo-enzymatic oxidation-reduction procedure

被引：28

作者：

Enright, A

Alexandre, FR

Roff, G

Fotheringham, IG

Dawson, MJ

Turner, NJ

机构：

[1] Univ Edinburgh, Sch Chem, Edinburgh EH9 3JJ, Midlothian, Scotland

[2] GlaxoSmithKline R&D, Med Res Ctr, Stevenage SG1 2NY, Herts, England

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 20期

关键词：

D O I：

10.1039/b309787k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Both D- and L-beta- and gamma-substituted alpha-amino acids can be interconverted to their respective L- and D-diastereoisomers by treatment with an enantioselective amino acid oxidase and a chemical reducing agent.

引用

页码：2636 / 2637

页数：2

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