Construction of a Structurally Defined Double-Stranded DNA Catenane

被引：98

作者：

Schmidt, Thorsten L. ^{[1
]}

Heckel, Alexander ^{[1
]}

机构：

[1] Goethe Univ Frankfurt, D-60438 Frankfurt, Germany

来源：

NANO LETTERS | 2011年 / 11卷 / 04期

关键词：

DNA nanotechnology; catenanes; topology; topologically interlocked structures; self-assembly; KNOTS; NANOSTRUCTURES; MINICIRCLES; POLYAMIDES; ROTAXANE; RINGS;

D O I：

10.1021/nl200303m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Topologically interlocked structures like catenanes and rotaxanes are promising components for the construction of molecular machines and motors. Herein we describe the construction of double-stranded DNA catenanes for DNA nanotechnology. For this, C-shaped DNA minicircle fragments were equipped with sequence-specific DNA-binding polyamides and their respective binding site. Formation of catenanes is achieved by self-assembly of two of these fragments and subsequent addition of a ring-closing oligonucleotide.

引用

页码：1739 / 1742

页数：4

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