Multicomponent synthesis of spiroisoxazolines

被引：72

作者：

Adamo, MFA

Donati, D

Duffy, EF

Sarti-Fantoni, P

机构：

[1] Royal Coll Surgeons Ireland, Ctr Synth & Chem Biol, Dept Pharmaceut & Med Chem, Dublin 2, Ireland

[2] Univ Siena, Dipartimento Chim, I-53100 Siena, Italy

[3] Univ Florence, Dipartimento Chim Organ U Schiff, I-50019 Sesto Fiorentino, Italy

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 21期

关键词：

D O I：

10.1021/jo051181w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A three-component one-pot procedure (3-MCR) was developed to assemble the spiroisoxazoline nucleus from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chromatography.

引用

页码：8395 / 8399

页数：5

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