Well-defined and easily accessible yttrium complexes for enantioselective cyclisation of amines tethered to 1,2-di-substituted alkenes

被引：43

作者：

Chapurina, Yulia ^{[1
,2
]}

Hannedouche, Jerome ^{[1
,3
]}

Collin, Jacqueline ^{[1
,3
]}

Guillot, Regis ^{[3
]}

Schulz, Emmanuelle ^{[1
,3
]}

Trifonov, Alexander ^{[2
]}

机构：

[1] Univ Paris 11, Equipe Catalyse Mol, ICMMO, UMR 8182, F-91405 Orsay, France

[2] Russian Acad Sci, GA Razuvaev Inst Organomet Chem, Nizhnii Novgorod 603600, Russia

[3] CNRS, F-91405 Orsay, France

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 37期

关键词：

ASYMMETRIC INTRAMOLECULAR HYDROAMINATION; AMIDATE COMPLEXES; CATALYSTS;

D O I：

10.1039/c0cc01064b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A straightforward in situ preparation of new chiral amido alkyl ate yttrium complexes is described. They catalysed the enantioselective cyclisation of 1,2-dialkyl-substituted aminopentenes in up to 77% ee, a significant value for this challenging transformation. Complex [(R)-L-0][Y(CH2TMS)(2)center dot Li(THF)(4)] undergoes C-H bond activation resulting in the formation of an original dimeric heterobimetallic yttrium complex which also acts as an active precatalyst.

引用

页码：6918 / 6920

页数：3

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