Wolbachia pipientis: an expanding bag of tricks to explore for disease control

被引：35

作者：

Cook, Peter E. ^{[1
]}

McGraw, Elizabeth A. ^{[1
]}

机构：

[1] Univ Queensland, Sch Biol Sci, Brisbane, Qld, Australia

来源：

TRENDS IN PARASITOLOGY | 2010年 / 26卷 / 08期

基金：

英国医学研究理事会; 美国国家卫生研究院;

关键词：

LIFE-SHORTENING WOLBACHIA; INFECTION; SYMBIONT; DROSOPHILA; VIRULENT;

D O I：

10.1016/j.pt.2010.05.006

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus and Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies and evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.

引用

页码：373 / 375

页数：3

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