GATA factors in Drosophila heart and blood cell development

被引:46
作者
Sorrentino, RP [1 ]
Gajewski, KM [1 ]
Schulz, RA [1 ]
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Biochem & Mol Biol, Houston, TX 77030 USA
关键词
Drosophila heart development; hemocyte lineage specification; pannier; serpent; U-shaped;
D O I
10.1016/j.semcdb.2004.10.005
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
GATA transcription factors comprise an evolutionarily conserved family of proteins that function in the specification and differentiation of various cell types during animal development. In this review, we examine current knowledge of the structure, expression, and function of the Pannier and Serpent GATA factors as they relate to cardiogenesis and hematopoiesis in the Drosophila system. We also assess the molecular and genetic characteristics of the Friend of GATA protein U-shaped, which serves as a regulator of Pannier and Serpent function in these two developmental processes. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:107 / 116
页数:10
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