Electrospinning of methoxy poly(ethylene glycol)-grafted chitosan and poly(ethylene oxide) blend aqueous solution

被引：38

作者：

Han, Jing ^{[1
]}

Zhang, Jianfeng ^{[1
]}

Yin, Ruixue ^{[1
]}

Ma, Guiping ^{[1
]}

Yang, Dongzhi ^{[1
]}

Nie, Jun ^{[1
,2
]}

机构：

[1] Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Key Lab Beijing City Preparat & Proc Novel Polyme, Beijing 100029, Peoples R China

[2] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China

来源：

CARBOHYDRATE POLYMERS | 2011年 / 83卷 / 01期

关键词：

Electrospinning; Chitosan; Poly(ethylene oxide); Nanofibers; PEG-GRAFTED CHITOSAN; TISSUE ENGINEERING APPLICATIONS; THERMOSENSITIVE HYDROGEL; GLYCOL); DERIVATIVES; WATER; NANOFIBERS; COPOLYMERS; DELIVERY; ESTER;

D O I：

10.1016/j.carbpol.2010.07.057

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Methoxy poly(ethylene glycol)-grafted chitosan (PEG-g-CS) was synthesized by mild Michael addition reaction of chitosan and methoxy polyethylene glycol monoacrylate. The chemical structure and degree of substitution (DS) of chitosan derivative were studied by FT-IR and H-1 NMR. Blend nanofibers of PEG-g-CS and poly(ethylene oxide) (PEO) were successfully fabricated by electrospinning and characterized by SEM, XRD, DSC and TEM. SEM images showed when the mass ratio of PEG-g-CS/PEO ranged from 4/1 to 1/2, uniform ultrafine fibers could be fabricated. XRD and DSC results confirmed the crystalline microstructure of PEO component. The core-shell structure nanofibers were observed by TEM. Besides, water resistance of glutaraldehyde crosslinked nanofibers and organic solvent resistance of original nanofibers were also evaluated through morphology analysis. (C) 2010 Published by Elsevier Ltd.

引用

页码：270 / 276

页数：7

共 34 条

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