Synthesis of 9-propyl-10-azacyclododecan-12-olide

被引：6

作者：

King, AG

Meinwald, J

Eisner, T

Blankespoor, CL

机构：

[1] CORNELL UNIV, DEPT CHEM, ITHACA, NY 14853 USA

[2] CORNELL UNIV, NEUROBIOL SECT, ITHACA, NY 14853 USA

[3] CALVIN COLL, DEPT BIOL, GRAND RAPIDS, MI 49546 USA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 13期

关键词：

D O I：

10.1016/0040-4039(96)00233-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

9-Propyl-10-azacyclododecan-12-olide, a minor component of the defensive secretion of the Mexican bean beetle (Epilachna varivestis) was synthesized via a reductive amination of methyl 9-ketododecanoate (3) followed by lactonization. This azamacrolide proved deterrent to ants, but was significantly less active than the pupal defensive secretion itself.

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页码：2141 / 2144

页数：4

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