Synthesis of new chiral monodentate phosphite ligands and their use in catalytic asymmetric hydrogenation

被引:78
作者
Hua, ZH [1 ]
Vassar, VC [1 ]
Ojima, I [1 ]
机构
[1] SUNY Stony Brook, Dept Chem, Stony Brook, NY 11794 USA
关键词
D O I
10.1021/ol035343r
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] New monodentate phosphite ligands have been developed from axially chiral biphenols, which show excellent enantioselectivity in the Rh-(I)-catalyzed hydrogenation of dimethyl itaconate. The new chiral ligand system is suitable to create libraries and possesses fine-tuning capability.
引用
收藏
页码:3831 / 3834
页数:4
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