Emerging Advances in Rapid Diagnostics of Respiratory Infections

被引：24

作者：

Murdoch, David R. ^{[1
,2
]}

Jennings, Lance C. ^{[1
,2
]}

Bhat, Niranjan ^{[3
]}

Anderson, Trevor P. ^{[2
]}

机构：

[1] Univ Otago Christchurch, Dept Pathol, Christchurch 8140, New Zealand

[2] Canterbury Hlth Labs, Microbiol Unit, Christchurch 8140, New Zealand

[3] Johns Hopkins Sch Med, Div Infect Dis, Dept Pediat, Baltimore, MD 21287 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2010年 / 24卷 / 03期

基金：

比尔及梅琳达.盖茨基金会; 美国国家卫生研究院;

关键词：

Respiratory infection; Pneumonia; Polymerase chain reaction; Diagnostics; Antigen detection; POLYMERASE-CHAIN-REACTION; COMMUNITY-ACQUIRED PNEUMONIA; REAL-TIME PCR; INFLUENZA-A H1N1; BRONCHOALVEOLAR LAVAGE FLUIDS; EXHALED BREATH CONDENSATE; SYNCYTIAL VIRUS; ELECTRONIC NOSE; STREPTOCOCCUS-PNEUMONIAE; LABORATORY DIAGNOSIS;

D O I：

10.1016/j.idc.2010.04.006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recent developments in rapid diagnostics for respiratory infections have mostly occurred in the areas of antigen and nucleic acid detection. Nucleic acid amplification tests have improved the ability to identify respiratory viruses in clinical specimens and have played pivotal roles in the rapid characterization of new viral pathogens. Antigen-detection assays in immunochromatographic or similar formats are most easily developed as near-patient tests, although they have been developed commercially only for a limited range of respiratory pathogens. New approaches for respiratory pathogen detection are needed, and breath analysis is an exciting area with enormous potential.

引用

页码：791 / +

页数：18

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