Transcranial Brain Stimulation: Clinical Applications and Future Directions

被引:43
作者
Najib, Umer [1 ]
Bashir, Shahid [1 ]
Edwards, Dylan [1 ,2 ]
Rotenberg, Alexander [1 ,3 ]
Pascual-Leone, Alvaro [1 ,4 ]
机构
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Neurol,Berenson Allen Ctr Noninvas Brain Sti, Boston, MA 02215 USA
[2] Burke Med Res Inst Inc, Noninvas Brain Stimulat & Human Motor Control Lab, White Plains, NY 10605 USA
[3] Harvard Univ, Sch Med, Childrens Hosp, Div Epilepsy & Clin Neurophysiol,Dept Neurol, Boston, MA 02115 USA
[4] Univ Autonoma Barcelona, Inst Univ, Inst Guttman Neurorehabil, Badalona 08916, Spain
关键词
Transcranial brain stimulation; Brain mapping; Transcranial magnetic stimulation; Functional neuroimaging; PRIMARY MOTOR CORTEX; CORTICAL HAND REPRESENTATION; FOCAL NEOCORTICAL EPILEPSY; MAGNETIC STIMULATION; PARKINSONS-DISEASE; EVOKED-POTENTIALS; TUMOR SURGERY; CORTICOSPINAL EXCITABILITY; INTRACTABLE EPILEPSY; PROGNOSTIC VALUE;
D O I
10.1016/j.nec.2011.01.002
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Noninvasive brain stimulation is a valuable investigative tool and has potential therapeutic applications in cognitive neuroscience, neurophysiology, psychiatry, and neurology. Transcranial magnetic stimulation (TMS) is particularly useful to establish and map causal brain-behavior relations in motor and nonmotor cortical areas. Neuronavigated TMS is able to provide precise information related to the individual's functional anatomy that can be visualized and used during surgical interventions and critically aid in presurgical planning, reducing the need for riskier and more cumbersome intraoperative or invasive mapping procedures. This article reviews methodological aspects, clinical applications, and future directions of TMS-based mapping.
引用
收藏
页码:233 / +
页数:20
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