Actin dynamics: Assembly and disassembly of actin networks

被引：116

作者：

Wear, MA ^{[1
]}

Schafer, DA ^{[1
]}

Cooper, JA ^{[1
]}

机构：

[1] Washington Univ, Dept Cell Biol & Physiol, St Louis, MO 63110 USA

来源：

CURRENT BIOLOGY | 2000年 / 10卷 / 24期

关键词：

D O I：

10.1016/S0960-9822(00)00845-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Assembly of branched actin filament networks at the leading edge of migrating cells requires stimulation of the Arp2/3 complex by WASp proteins, in concert with the WASp activators Cdc42, PIP2 and profilin, Network disassembly and debranching appears to be linked to actin bound ATP hydrolysis as filaments age.

引用

收藏

页码：R891 / R895

页数：5

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