Convergent synthesis and preliminary biological evaluations of the stilbenolignan (±)-aiphanol and various congeners

被引：15

作者：

Banwell, MG ^{[1
]}

Bezos, A

Chand, S

Dannhardt, G

Kiefer, W

Nowe, U

Parish, CR

Savage, GP

Ulbrich, H

机构：

[1] Australian Natl Univ, Inst Adv Studies, Res Sch Chem, Canberra, ACT 0200, Australia

[2] Australian Natl Univ, Inst Adv Studies, John Curtin Sch Med Res, Canberra, ACT 0200, Australia

[3] Univ Mainz, Inst Pharm, D-55099 Mainz, Germany

[4] CSIRO Mol Sci, Clayton S MDC, Vic 3169, Australia

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2003年 / 1卷 / 14期

关键词：

D O I：

10.1039/b305106d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of an equimolar mixture of stilbene 7 and cinnamyl alcohol 8 with silver carbonate in acetone-benzene afforded a ca. 2 : 1 : 2 : 1 mixture of the stilbenolignan (+/-)-aiphanol (1) and congeners 2-4 each of which show significant anti-angiogenic and COX-2 inhibitory properties.

引用

页码：2427 / 2429

页数：3

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